Cross-reactive Carbohydrate Determinant Contributes to the False Positive IgE Antibody to Peanut
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چکیده
منابع مشابه
Cross-reactive Carbohydrate Determinant Contributes to the False Positive IgE Antibody to Peanut
Background: The importance of peanut allergy has not been well recognized in Japanese society. IgE antibody to peanut can be, however, detected in patients without clinical peanut allergy. Methods: Clinical characteristics of 14 patients (aged 1―8 years) with peanut allergy were evaluated. IgE antibodies to peanut from patients with and without clinical peanut allergy were compared with those t...
متن کاملPeanut-specific IgE antibodies in asymptomatic Ghanaian children possibly caused by carbohydrate determinant cross-reactivity
BACKGROUND The prevalence of peanut allergy has increased in developed countries, but little is known about developing countries with high peanut consumption and widespread parasitic infections. OBJECTIVE We sought to investigate peanut allergy in Ghana. METHODS In a cross-sectional survey among Ghanaian schoolchildren (n = 1604), data were collected on reported adverse reactions to peanut,...
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BACKGROUND Allergy diagnosis by determination of allergen-specific IgE is complicated by clinically irrelevant IgE, of which the most prominent example is IgE against cross-reactive carbohydrate determinants (CCDs) that occur on allergens from plants and insects. Therefore, CCDs cause numerous false-positive results. Inhibition of CCDs has been proposed as a remedy, but has not yet found its wa...
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Emerging data suggest that measurement of serum IgE to peanut components can be clinically helpful and more accurate than IgE to whole peanut to predict peanut allergy. Not all studies have used prospective samples, multiple components and oral challenges. Currently, there are no data on this topic involving Italian children. 32 patients (23 males; median age 9 years) with reported history for ...
متن کاملEvaluation of IgE antibodies to recombinant peanut allergens in patients with reported reactions to peanut.
BACKGROUND Peanut may cause severe reactions in allergic individuals. The objective was to evaluate IgE antibodies to various recombinant (r) peanut and birch pollen allergens in relation to IgE levels to whole peanut extract and severe allergic reactions to peanut. METHODS Seventy-four Swedish peanut-allergic patients (age: 14-61 years) reported previous peanut exposure and associated sympto...
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ژورنال
عنوان ژورنال: Allergology International
سال: 2005
ISSN: 1323-8930
DOI: 10.2332/allergolint.54.387